Want to slow aging? You might want to ditch the moisturizer and eat less.
Scientists at Brigham Young University have published research that show cutting calories affects aging inside a cell. They found that ribosomes — the cell’s protein maker — slow down when calories were cut and that, in turn, this calorie-restriction led to longer, healthier lives in mice.
“When you restrict calorie consumption, there’s almost a linear increase in lifespan,” Brigham Young University biochemistry professor and senior author John Price told Science Daily. “We inferred that the restriction caused real biochemical changes that slowed down the rate of aging.”
The research, published in Molecular & Cellular Proteomics, includes the study of two groups of mice, one with unlimited access to food, the other restricted to consume 35 percent fewer calories, but still receiving all the necessary nutrients for survival. Ribosomes slowed down in the group on a restricted diet, apparently slowing the cellular process of aging as well. The calorie-restricted mice were also more energetic.
Other studies have shown a connection between fewer calories and longer lifespan, but the Brigham Young team is “the first to show that general protein synthesis slows down and to recognize the ribosomes role in facilitating those youth-extending biochemical changes.”
Ribosomes use about 10 to 20 percent of a cell’s total energy to build the proteins that allow the cell to function. When ribosomes slow down at their jobs, it gives them more time to repair themselves.
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Read full article at: http://herald-review.com/fewer-calories-may-lead-to-longer-life/article_97dc43ea-8afc-5529-bfc8-352064c408c8.html
Related article: Biochemistry Help Online
Scientists at Brigham Young University have published research that show cutting calories affects aging inside a cell. They found that ribosomes — the cell’s protein maker — slow down when calories were cut and that, in turn, this calorie-restriction led to longer, healthier lives in mice.
“When you restrict calorie consumption, there’s almost a linear increase in lifespan,” Brigham Young University biochemistry professor and senior author John Price told Science Daily. “We inferred that the restriction caused real biochemical changes that slowed down the rate of aging.”
The research, published in Molecular & Cellular Proteomics, includes the study of two groups of mice, one with unlimited access to food, the other restricted to consume 35 percent fewer calories, but still receiving all the necessary nutrients for survival. Ribosomes slowed down in the group on a restricted diet, apparently slowing the cellular process of aging as well. The calorie-restricted mice were also more energetic.
Other studies have shown a connection between fewer calories and longer lifespan, but the Brigham Young team is “the first to show that general protein synthesis slows down and to recognize the ribosomes role in facilitating those youth-extending biochemical changes.”
Ribosomes use about 10 to 20 percent of a cell’s total energy to build the proteins that allow the cell to function. When ribosomes slow down at their jobs, it gives them more time to repair themselves.
s
Read full article at: http://herald-review.com/fewer-calories-may-lead-to-longer-life/article_97dc43ea-8afc-5529-bfc8-352064c408c8.html
Related article: Biochemistry Help Online
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